Endocrine Abstracts

Introduction: The adrenocortical carcinoma (ACC) is a primary malignant tumor developed in depends of the adrenal cortex, defined by a Weiss score ≥3. Despite the therapeutic progress, its prognosis is still severe.Patients and methods: This retrospective descriptive study evaluated 4 patients with adrenal corticosteroid followed in the endocrinology department of Sfax - Tunisia between 2010 and 2018.Results: There were 3 wom...

Introduction: Paragangliomas are rare endocrine tumors that represent extra-adrenal localization of pheochromocytomas. Signs of catecholamine excess are the most found manifestation of this tumor especialy hypertension. However, paragangliomas can be asymptomatic or can manifest with nonspecific signs. The association between pheochromocytomas and inflammatory diseases is exceptional.Observation: Here we report the case of a 26 years old male that was ad...

Introduction: Pheochromocytoma is a rare tumor of adrenal gland tissue that is responsible for secondary hypertension and other clinical manifestations resulting from catecholamine excess and it can result in severe damage to other body systems, especially the cardiovascular system. Here we report an atypical presentation of pheochromocytoma.Presentation: A 40 years old female patient that was admitted into the internal medicine ward with acute ischemia ...

Introduction: Hyperparathyroidism is defined by excessive secretion of parathyroid hormone (PTH) that is responsible for calcium regulation. Hyperparathyroidism can be primary in which the gland is affected and it produces PTH excessively or secondary or tertiary that cause hypersecretion of PTH as a regulatory response. The aim of our study was to describe patients with hyperparathyroidise diagnosed in internal medicine departement.Methods: It was a ret...

Introduction: Graves’ disease is an autoimmune disease that affects the thyroid gland and leads to a state of hyperthyroidism. This disease is caused by the production of antibodies that bind to and activate the thyroid-stimulating hormone (TSH) receptor. In some cases, Grave’ disease may be associated with other organ-specific or systemic autoimmune disorders. One of the most frequent multisystemic autoimmune disorders is Systemic lupus erythematosus (SLE). Many s...

Introduction: Hyperpigmentation is a clinical sign that can be associated with different endocrine disorders. It is commonly seen in Addison’s disease and has rarely been reported in Graves’ disease. The exact physio pathological mechanism of this sign is not well established in hyperthyroidism. We describe two cases of Graves’ disease accompanied by diffuse hyperpigmentation.Case report: Case 1 was a 63-year-old female ad...

Introduction: Moyamoya disease is a rare angiopathy characterized by a progressive stenosis of the intracranial internal carotid arteries (ICA). First described in 1957, its pathophysiological mechanisms are still not well understood. Its association with various systemic diseases is termed moyamoya syndromeObservation: A 21-year-old female patient, with a family history of hypothyroidism, was admitted initially with stroke. The clinical examination reve...

Introduction: Pituitary neuroendocrine tumors (PitNET) represent 15.5% of primary brain tumors and they can be clinically functioning or non-functioning. Although they are mostly benign, PitNET may be invasive in 30-45% of cases and aggressive in at least 15%. Here, we report the case of a patient who presented a multiple and rapid recurrence of a non-functional pituitary macroadenoma.Observation: A 42-year-old man was admitted initially for headaches, m...

Introduction: Thyroid-associated orbitopathy is an autoimmune disease of the retroocular tissues commonly associated with Graves’ disease (GD) and rarely reported in Hashimoto’s thyroiditis (HT). GD and HT are autoimmune thyroid disease which are sometimes hard to distinguish from one another and their association in one person is rarely described. Here, we report a case of an exacerbation of thyroid-associated orbitopathy in a patient with GD following a SARS-CoV-2 ...

Introduction: Hypertension disorders during pregnancy constitute a significant cause of maternal and perinatal mortality worldwide. Paragangliomas represent a rare cause of hypertension in gestation. The management of these endocrine tumors can be challenging, especially when diagnosed during pregnancy. We describe a case of a paraganglioma discovered in a pregnant woman.Case report: We report the case of a twenty-seven-year-old female patient who presen...